We are welcoming Prof. Dr. Marc Nowaczyk from the University of Rostock, who will give a guest lecture about „Structure and function of cyanobacteria membrane protein complexes“ on March 13, 2024 at 12:30 in the Biocenter (N100/0.15). Afterwards, he will stay for a career talk with the MAPS students.


We are very pleased that Prof. Dr. Inga Hänelt, principal investigator of CRC project 4 and head of the IRTG, has been honored by the Goethe University for her exceptional research and strong commitment to the promotion of young researchers receiving the award „Scientist of the Year“ donated by the Alfons & Gertrud Kassel-Stiftung. Congratulations!


Our next Günter Blobel Lecture takes place on November 15th 2023 at 12:30 noon in the Biocenter: Prof. Dr. Marek Basler from the University of Basel will present his work on „Spatial and temporal regulation of Type 6 Secretion System dynamics during interactions with bacterial and eukaryotic cells“. In the afternoon, Prof. Basler will meet up with the MAPS students for a career talk.


Dr. Bonnie J. Murphy (project 15) has been awarded an ERC Starting Grant for her innovative research to determine structures of proteins involved in the cellular energy metabolism. Congratulations!


We are happy to announce that Prof. Dr. Min Chen from the University of Massachusetts Amherst visits Frankfurt for a guest lecture about „Nanopore biosensing: From proteomics, genomics, and drug discovery“ on July 14th 2023 at 12:30 in the Biocenter (seminar room N100/015).


A publication from project P18 about the activation of the immune system by dendritic cells has been featured on the homepage of Goethe University Frankfurt: 


Prof. Dr. Michael Schlame from New York University Langone Health is welcomed in the Biocenter to give a guest lecture about „Why do mitochondria need cardiolipin?“ on July 5th 2023 at 13:00 in lecture hall B3.


The CRC’s Günter Blobel Lecture Series continue with Prof. Dr. Gary Rudnick from Yale University School of Medicine and his guest lecture on „Conformational change in NSS transporters: Roles in ion-substrate coupling and drug design“, on June 16th 2023 (11:30 am) in the Biocenter’s seminar room N100/114.


We are welcoming our next guest speaker on June 2nd 2023: Prof. Dr. Attilio V. Vargiu from the University of Cagliari will present his work on „A computational protocol to generate druggable protein conformations“ at 12:30 in the Biocenter (seminar room N100/015).


The successful collaboration within CRC projects P12 and P17 led to an exciting publication in Nature about the determination of unknown molecular structures inside the central transport channel of the mammalian nuclear pore complex. Utilizing a combination of microscopy and molecular simulations, a dynamic protein network at the center of the pore is identified which acts as a flexible transport barrier selectively letting pass messengers and blocking pathogens. („Visualizing the disordered nuclear transport machinery in situ“,

April 2023

A structure from our CRC has been highlighted as Molecule of the Month at RCSB Protein Data Bank ( 


On Thursday, April 6th at 10:30, Prof. Dr. Jonathan A. Javitch from Columbia University will talk about „Deciphering mechanisms of activation in metabotropic glutamate receptor heterodimers“ (Biocenter, seminar room N100/015).


The CRC 1507 hosts an Early Career Group Leader Symposium on Thursday, March 30th, 2023 (10:00 am). This event gathers intriguing young scientists and is the start of the CRC‘s newly established Günter Blobel Lecture Series. The connection of Günter Blobel to the Institute of Biochemistry started during his studies of Medicine/Biochemistry in Frankfurt and was revived in 2002 during his honorary Rolf-Sammet Professorship at Goethe University.


Dr. Niels Fischer from the Max Planck Institute for Multidisciplinary Sciences in Göttingen visits our CRC for scientific exchange of advances in single-particle cryo-EM and will give a guest lecture about „Visualizing the dynamic machinery of translation initiation in humans“ in the Biocenter on March 9th, 2023 at 13:00.


Much looking forward to Dr. Katia Cosentino (Molecular Cell Biophysics, University of Osnabrück) and her talk on „Membrane pores in cell death: from pore assembly to structure by single-molecule approaches“. Guests are welcome to join the lecture on Feb 1st, 2023 at 13:15 in the Biocenter.


Happy to announce the first guest lecture of 2023: On Wednesday, Jan 18th at 13:00 c.t., Prof. Dr. Rose-John from Biochemistry Department of Christian Albrechts University Kiel will give a lecture (Biocenter, seminar room 0.15) on „Interleukin-6 and ADAM17: Proteolysis, Pathophysiology and Implications for Therapy of Autoimmune Disease“.


We are very delighted that Dr. Bonnie J. Murphy, principal investigator of project 15, has been granted a membership of the EMBO Young Investigator Programme. She is one of 24 life scientists who will join the EMBO Young Investigator network and receive financial and practical support for a period of four years. We compliment Bonnie on joining this programme for excellent group leaders.


We are excited to announce that Prof. Dr. Sabine Petry, Dept of Molecular Biology, Princeton University, will talk about „How to make microtubules and build the cytoskeleton“ on Thursday, 11/17/2022 at 11:30 am (s.t.) at the Goethe University Biozentrum, seminar room 0.15 (check Twitter news for the remote access).


In the frame of the seminar series of the CRC, we are happy to announce that Prof. Dr. Blanche Schwappach-Pignataro, Dean of the University Medical Center Hamburg, will visit us for a lecture. Her lecture „GETting to the Endoplasmic Reticulum – Hairpin proteins as non-canonical targeting clients of the ‚Guided Entry for Tail-anchored proteins‘ pathway“ will take place on Monday, 10/31/2022 at 11 am at the Goethe University Biozentrum (check notices for the lecture hall).


The CRC proudly welcomed its first guest lectures in the Biocenter of Goethe University. Prof. Stephanie Gras and Dr. Christopher Szeto from the Gras Lab at La Trobe University came all the way from Australia to talk about „Fight against COVID-19: functional and structural study of the T cell response“.

X (Twitter)

A publication on “Structure and assembly of a bacterial gasdermin pore” has recently been released in Nature (). Congratulations to Stefan Schäfer and Gerhard Hummer (Project 12) for this successful cooperation with the Kranzusch group / Harvard University!

Happy to welcome Prof. Dr. Marc Nowaczyk from the University of Rostock giving a guest lecture about “Structure and function of cyanobacterial membrane protein complexes” on March 13, 2024 (12:30, N100/0.15).
Link for remote access:

✨Wishing you a Merry Christmas and a good start into the New Year - may your holiday season be filled with peace and kindness ✨ We are looking forward to upcoming scientific lectures, events and discussions in 2024

We're proud of the head of our Graduate School, Inga Hänelt, who just received the Goethe University Scientist of the Year Award in recognition of her outstanding research achievements and, in particular, the promotion of young scientists. Congrats Inga and keep up the good work!

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